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We have collated a selection of scientific evidence for non-surgical cosmetic procedures we carry out at Skin Tech Clinic.  These present accurate data relating to the effectiveness of the procedures we carry out. If you wish to read more about the topics, we have listed the journal and authors names to assist you in your research. It is important that you are informed before deciding to take treatment and we believe that these journal articles will help you in your decision.

Safety, Tolerance, and patient Satisfaction with Non-invasive Cryolipolysis  – Christine C. Dierickx, Jean- Michel Mazer, Mila Sand, Sylvie Koenig, And Valerie Arigon

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This research concluded that with proper patient selection, cryolipolysis is a safe, well-tolerated, and effective treatment method for reduction of subcutaneous fat. “The investigators treated 518 patients. No significant side effects or adverse events were reported. The procedure was well tolerated, with 89% of respondents reporting a positive perception of treatment duration and 96% reporting minimal to tolerable discomfort. Survey results demonstrated 73% patient satisfaction and that 82% of patients would recommend the cryolipolysis procedure to a friend. Caliper measurements demonstrated 23% reduction in fat layer thickness at 3 months. Abdomen, back, and flank treatment sites were most effective, with 86% of subjects showing improvement per investigator assessment”

Journal: Cryolipolysis (fat freeze) for subcutaneous Fat layer Reduction – Mathew M. Avram, MD, JD1 and Rosemary S. Harry, MSBME2

Link to the research paper:

This research found that the efficacy and safety of this non-invasive procedure for fat layer reduction has been demonstrated in the studies available to date. “Cryolipolysis has demonstrated efficacy in both human and animal studies. Histology findings also confirm the selective reduction of fat in both humans and animals, with evidence of a gradual thinning of the fat layer over a period of two to four months. Importantly, cryolipolysis has not produced any significant adverse side effects in studies to date and any noted effects have been minor and temporary”


Journal: Synergistic Effects of Cryolipolysis and Shock waves for Non invasive Body Contouring – G. A. Ferraro, F. De Francesco, C. Cataldo, F. Rossano, G. Nicoletti, F. D’Andrea

Link to research paper:

The findings of this study show that Ice-Shock Lipolysis is an effective, safe and well-tolerated non-invasive procedure for body contouring. “The procedure significantly reduced the circumference in the treated areas, significantly diminishing fat thickness. The mean reduction in fat thickness after treatment was 3.02 cm. Circumference was reduced by a mean of 4.45cm. Weight was unchanged during the treatment, and no adverse effects were observed. Histologic and immunohistochemical analysis confirmed a gradual reduction of fat tissue by programmed cell death. Moreover, the reduction in thickness was accompanied by a significant improvement in microcirculation, and thus, the cellulite. The safety of the method also has been highlighted because it is accompanied by no significant increase in serum liver enzymes or serum lipids”


Journal: Non Invasive Selective Cryolipolysis and Reperfusion Recovery for Localized natural Fat Reduction and Contouring – Gordon H. Sasaki, MD, FACS; Natalie Abelev, RN; and Ana Tevez-Ortiz, RN


This study concluded that non-invasive cryolipolysis results in a noticeable and predictable fat reduction within six months without signs of skin damage. “Thirty minutes into the cooling phase, sub-dermal temperatures of patients in the PSG declined precipitously from pre-treatment levels and remained low until the end of treatment. During recovery, sub-dermal temperatures of the only subject who received massage returned faster and to higher levels than the temperatures of subjects who did not receive massage. Patients in the CTG who were available for follow-up measurements at 6 months (n = 85) demonstrated an average fat reduction of 21.5% by caliper measurements; 6 random patients from this group also showed an average of 19.6% fat reduction by ultrasound imaging at 6 months. Global assessments were highest for the abdomen, hip, and brassiere rolls. Minimal side effects were observed, and patients experienced no significant downtime.”


Cryolipolysis Research Journal: Cryolipolysis for Non-invasive fat cell Destruction Initial Results from a pig model – Brian Zelickson, Barbara M. Egbert, Y Jessica Preciado, Z John Allison, Kevin Springer, Robert W. Rhoades, and Dieter Manstein

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“The treatments resulted in a significant reduction in the superficial fat layer without damage to the overlying skin. An inflammatory response triggered by cold-induced apoptosis of adipocytes preceded the reduction in the fat layer. Evaluation of lipids over a 3-month period following treatment demonstrated that cholesterol and triglyceride values remained normal.”



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